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KMID : 1159320130150030305
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Korean Journal of Vision Science
2013 Volume.15 No. 3 p.305 ~ p.313
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Comparison of Physical Properties of hydrogel contact lens on Artificial Tear Containing Povidone and Hyaluronic acid of hydrogel contact lens
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Cho Seon-Ahr
Sung A-Young
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Abstract
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Purpose: The impacts of artificial tear that is a common material for the treatment of dry eye including povidone and hyaluronic acid on the hydrogel contact lens were analyzed in various conditions. Methods: The cross-linking agent, EGDMA(ethylene glycol dimethacrylate) and HEMA (2-hydroxyethyl methacrylate) were determined to be used as the basic combination to produce a soft hydrogel contact lens. Also, 20% each of NVP (n-vinyl-2-pyrrolidone) and MMA (methyl methacrylate) were added to this combination for classification of water content. The copolymerized contact lenses were stored in artificial tear for 3, 5, 10 min. and 1, 2, 72hrs. respectively. Also, the physical properties such as water content and contact angel of produced contact lenses were measured. Results: The measurement of the physical properties of the Ref. sample for povidone showed that water content and contact angle were in the range of 27.22~48.13% and , respectively. Also, the measurement of Ref. sample for hyaluronic acid showed that water content and contact angle were in the range of 26.42~48.42% and respectively. In addition, the measurement of physical property after soaking into artificial tear containing povidone, the water content and contact angle were in the range of 26.10~47.90% and respectively. Also, in case of the measurement of sample soaked in hyaluronic acid, the water content and contact angle were in the range of 24.89~48.35% and , respectively. In case of povidone, the changes of the physical property with soaking time showed decrease of water content and increase of contact angle. For hyaluronic acid, the measurement showed the decrease of water content and contact angle. Conclusions: Artificial tear including povidone and hyaluronic acid influenced on water content and contact angle of a hydrogel contact lenses.
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KEYWORD
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Povidone, hyaluronic acid, water content, contact angle
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